For Muslims, or followers of Islam, the Quran is the actual Word of God revealed through the archangel Gabriel to the Prophet of Islam during the twenty-three-year period of his prophetic mission. It was revealed in the Arabic language as a sonoral revelation which the Prophet repeated to his companions. Arabic became therefore the language of Islam even for non-Arab Muslims. Under the direction of the Prophet, the verses and chapters were organized in the order known to Muslims to this day. There is only one text of the Quran accepted by all schools of Islamic thought and there are no variants.

The Quran is the central sacred reality of Islam. The sound of the Quran is the first and last sound that a Muslim hears in this life. As the direct Word of God and the embodiment of God's Will, the Quran is considered as the guide par excellence for the life of Muslims. It is the source of all Islamic doctrines and ethics. Both the intellectual aspects of Islam and Islamic Law have their source in the Quran. Perhaps there is no book revered by any human collectivity as much as the Quran is revered by Muslims. Essentially a religion of the book, Islam sees all authentic religions as being associated with a scripture. That is why Muslims call Christians and Jews the "people of the book".

Throughout all its chapters and verses, the Quran emphasizes the significance of knowledge and encourages Muslims to learn and to acquire knowledge not only of God's laws and religious injunctions, but also of the world of nature. The Quran refers, in a language rich in its varied terminology, to the importance of seeing, contemplating, and reasoning about the world of creation and its diverse phenomena. It places the gaining of knowledge as the highest religious activity, one that is most pleasing in God's eyes. That is why wherever the message of the Quran was accepted and understood, the quest for knowledge flourished.